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Cat. No. Product Name Target Signaling Pathways
T22012 7BIO

FLT; DYRK; Aurora Kinase Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
7BIO 是靛玉红的衍生物,抑制细胞周期蛋白依赖性激酶5 和糖原合酶激酶-3β。它抑制 Aβ 寡聚体诱导的神经炎症、突触损伤、tau 过度磷酸化、星形胶质细胞和小胶质细胞的活化,并减轻 Aβ 寡聚体诱导的小鼠认知障碍。
T70075 KDS2010 mesylate

KDS2010 is a potent, highly selective, and reversible MAO-B inhibitor which shows 12,500-fold selectivity over MAO-A. KDS2010 overcomes the disadvantages of the irreversible MAO-B inhibitor and significantly attenuates increased astrocytic GABA levels and astrogliosis, thereby enhancing synaptic transmission, and rescuing learning and memory impairments in APP/PS1 mice.

化合物

7BIO
Cat.No: T22012
Synonym:
Target: FLT, DYRK, Aurora Kinase
KDS2010 mesylate
Cat.No: T70075
Synonym:
Target:
TargetMol Loading
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